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Patient Education

Taking Charge: How Is Breast Cancer Diagnosed?

Related Conditions
Breast Cancer
Ovarian Cancer

If you find a lump in your breast, notice changes in breast skin, find a swollen lymph node in your armpit, develop a nipple discharge, or if your doctor finds an abnormality on a screening mammogram, you will need to have tests to find out if you have breast cancer.

  • Diagnostic mammography. Diagnostic mammograms focus on a specific area of the breast. A number of different views may be taken, including some that magnify the abnormality.
  • Breast ultrasound. Ultrasound, also called sonography, uses high-frequency sound waves to outline a part of the body. No radiation is involved in the procedure. Ultrasound is most often used to distinguish a solid mass from a cyst. It may also be used to guide a breast biopsy.
  • Ductogram. This X-ray test can be helpful in finding the cause of a nipple discharge. A fine plastic tube is placed into the opening of the duct at the nipple. A small amount of contrast dye is injected, which outlines the shape of the duct when an X-ray image is taken.
  • Magnetic resonance imaging (MRI). Doctors are just starting to learn about how this imaging tool can be used to evaluate breast cancer. Your physician may recommend that you have a MRI of the breast, usually as part of a research study, to add to the information available from other tests.
  • Nipple discharge examination. Some of the fluid may be collected and examined under a microscope to see if cancer cells are present. A red or red-brown discharge suggesting blood may be due to cancer. A clear or milky secretion is very unlikely to be cancer.
  • Biopsy. A biopsy, a procedure in which a tissue sample is taken, must be performed to make sure that you have cancer. The diagnosis will be made by looking at the biopsy specimen under a microscope. There are several ways of performing biopsies, depending on where the suspicious area is located and whether it can be felt or seen with mammograms or ultrasound.
Continue reading
  • Fine needle aspiration (FNA) biopsy. In this procedure, a thin needle is guided into the abnormal area of the breast and a small amount of fluid or tissue is drawn out. To guide the needle, the physician will either palpate (feel) the lump, or use ultrasound.
  • Core needle biopsy. This type of biopsy uses a larger needle than FNA. It removes a small cylinder of tissue from the breast abnormality. If the lump can be felt, it is performed with local anesthesia in the doctor's office. The needle is guided into position in the same way as for a FNA.
    If the abnormality cannot be felt, a stereotactic core biopsy is performed with computerized mammography.
  • Surgical biopsy. Surgery may be needed to remove all or part of a lump for examination. An excisional biopsy removes all of the lesion, and a surrounding margin of normal-appearing tissue. This is usually performed in a hospital outpatient department with local anesthesia and a sedative.
    Sometimes the surgeon will have the radiologist mark the area right before surgery with a wire for localization. The area is numbed with local anesthetic and a thin hollow needle is placed with X-ray guidance in the suspicious area. Then a thin wire is inserted through the needle, with a small hook on the end to keep it in place. The needle is then removed and the wire is used to guide the surgeon to the area that must be removed.

Get a second opinion

It is recommended that you seek another doctor's opinion of your diagnosis and treatment choices. Getting a second opinion from a different breast cancer specialist can help you confirm your diagnosis and feel more confident in your treatment plan. Please check with your insurance company before seeking a second opinion to see if there are coverage limits.

Make sure you understand the information

If you are told you have breast cancer, you will feel overwhelmed with emotion and technical information. It is important and medically safe for you to take some time to make an informed choice about your treatment. Discuss with your doctor how soon you need to make your decision.

Bring someone along when you meet with your doctor to talk about your diagnosis and treatment. When you are emotionally upset, it can be hard to understand even simple information. Breast cancer treatment is not a simple subject.

Read more

  • Next section of Taking Charge: How Is Breast Cancer Treated?

Return to the Taking Charge index

  • What Is Breast Cancer?
  • Breast Cancer Risk Factors
  • If You Are at High Risk for Breast Cancer
  • Screening for Breast Cancer
  • How Is Breast Cancer Diagnosed?
  • How Is Breast Cancer Treated?
  • What Is Ovarian Cancer?
  • Who Gets Ovarian Cancer?
  • If You Are at High Risk for Ovarian Cancer
  • Screening for Ovarian Cancer
  • How Is Ovarian Cancer Diagnosed?
  • How is Ovarian Cancer Treated?
  • Living with Ovarian Cancer
  • Diet, Lifestyle and Cancer
  • Glossary of Terms

UCSF Health medical specialists have reviewed this information. It is for educational purposes only and is not intended to replace the advice of your doctor or other health care provider. We encourage you to discuss any questions or concerns you may have with your provider.

Recommended reading

Basic Facts About Breast Health

Learn basic facts about breast health, including the development of breast cancer, its types and stages and guidelines from the American Cancer Society.

Breast Cancer Glossary

Check out our comprehensive Glossary of Breast Cancer terminology, which includes definitions of everything from AC chemotherapy to peripheral neuropathy.

Breast Cancer Risk Factors

Click now to find a summary of the factors that increase risk for developing breast cancer, including both factors that we cannot change and those we can.

Self-Care and Recovery

Self-Care and recovery resources including an Introduction to Lifestyle Change, Nutrition and Breast Cancer, Hydration: Water and Health, Meditation and more.

Follow-Up Care for Breast Cancer Patients

After patients have completed treatment for early stage breast cancer, one of the common questions is, "How should I best be monitored?" Learn more here.

Preparing for a Lumpectomy or Mastectomy

Learn how to prepare for a lumpectomy or mastectomy, including restrictions before surgery, what to bring to the hospital and more.

Menopause and Breast Cancer

Breast cancer treatment often causes women to enter menopause prematurely. Although each woman reacts to therapy individually, certain side effects are common.

Metastatic Breast Cancer: Diagnosis and Treatment

Metastatic breast cancer is cancer that originated in the breast and has spread to other organ systems in the body. Learn more here.

Navigating Your Path to Breast Care

Different services and information are needed at different points in breast health care and breast cancer treatment. Learn more here.

Osteoporosis and Breast Cancer

Women who have had breast cancer or are considered at high risk for developing breast cancer are at risk for developing osteoporosis. Learn more.

Radiation Therapy for Breast Cancer

The UCSF Carol Franc Buck Breast Care Center and the Department of Radiation Oncology have compiled information about radiation therapy for your convenience.

Related clinics

Breast Care Center

UCSF-Health John Muir Cancer Center in Berkeley

See all 6 of our Bay Area locations and learn more about the center.

Gynecologic Oncology Center

Bakar Precision Cancer Medicine Building

See all 3 of our Bay Area locations and learn more about the center.

(415) 353-9600
Did you know?

Cutting-edge techniques for mapping the human brain – developed by UCSF neurologists – help us locate language, motor and sensory functions and make surgery safer, more precise and less invasive. Brain mapping may one day lead to therapies for restoring healthy brain circuitry in patients with epilepsy, depression, stroke and other conditions.

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