Drugs Reported to Cause Priapism

In one-third of the cases, the cause of priapism is unknown. The remaining cases are caused by an associated condition, including sickle cell disease, pelvic tumors, pelvic infections, leukemia, genital trauma or spinal cord trauma. A variety of medications or recreational drugs also can lead to priapism.

Antidepressants

Bupropion
Trazodone
Fluoxetine
Sertraline and lithium

Antipsychotics

Clozapine

Antianxiety Agents

Hydroxyzine

Psychotropics

Chlorpromazine

Alpha-adrenergic Blocker

Prazosin

Hormones

Gonadotropin-releasing hormone (in hypogonadal men)
Testosterone

Anticoagulants

Heparin
Coumadin

Recreational Drugs

Cocaine
Alcohol

UCSF Health medical specialists have reviewed this information. It is for educational purposes only and is not intended to replace the advice of your doctor or other health care provider. We encourage you to discuss any questions or concerns you may have with your provider.

Related clinics

Urology Practice

400 Parnassus Ave., Sixth Floor, Suite A610
San Francisco, CA 94143

(415) 353-2200

M-F, 8 a.m. - 5 p.m.

Recommended reading

Erectile Dysfunction Causes

The greatest medical risk factors for erectile dysfunction include diabetes mellitus, heart disease, and hypertension. Learn more here.

Oral Medications for Erectile Dysfunction

Find a list of oral medications for Erectile Dysfunction (ED) including, viagra, levitra, and cialis and possible side effects and important things to remember.

Penile Injections: A Patient Guide

Although you probably find the idea of injecting something into your penis unappealing, many men are highly satisfied with this therapy. Learn why here.